The risk of non-Hodgkin's lymphoma after Hodgkin's disease, with special reference to splenic treatment.
作者: Enrici R MAnselmo A PIacari VOsti M FSantoro MTombolini VMandelli FBiagini C
作者单位: 1Department of Radiation Oncology, Policlinico Umberto I, La Sapienza University of Rome, Italy.
刊名: Haematologica, 1998, Vol.83 (7), pp.636-44
来源数据库: PubMed Journal
原始语种摘要: BACKGROUND AND OBJECTIVE(#br)One of the consequences of the enormous improvement in survival rates of patients treated for Hodgkin's disease (HD) is the emergence in the long term of treatment-related complications, particularly secondary cancers. This study was undertaken to observe the occurrence of non-Hodgkin's lymphoma (NHL) in patients treated for HD and to identify the etiological role of various risk factors, especially spleen irradiation, in the pathogenesis of this illness.(#br)DESIGN AND METHODS(#br)From 1972 to 1996, the Department of Radiation Oncology and the Hematology Section of "La Sapienza" University of Rome observed and analyzed the occurrence of NHL in 1,391 patients treated for HD. The average follow-up period was 84 months. For a more accurate calculation of the...
全文获取路径: PubMed  (合作)
影响因子:5.935 (2012)

  • lymphoma 淋巴瘤
  • splenic 脾的
  • treatment 处理
  • irradiation 照射
  • cumulative 累积的
  • splenectomy 脾切除术
  • occurrence 事件
  • salvage 废弃物
  • survival 生存
  • according 按照