Full genomic characterization of a porcine rotavirus strain detected in an asymptomatic piglet in Accra, Ghana.
作者: Stubbs Samuel C BQuaye OsbourneAcquah Maame EkuaAdadey Samuel MawuliKean Iain R LGupta SrishtiBlacklaws Barbara A
作者单位: 1Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
2West African Centre for Cell Biology of Infectious Pathogens (WACCBIP), Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Volta Road, P. O. Box LG 54, Legon, Accra, Ghana. oquaye@ug.edu.gh.
3West African Centre for Cell Biology of Infectious Pathogens (WACCBIP), Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Volta Road, P. O. Box LG 54, Legon, Accra, Ghana.
刊名: BMC veterinary research, 2020, Vol.16 (1), pp.11
来源数据库: PubMed Journal
DOI: 10.1186/s12917-019-2226-9
关键词: Full genome sequence constellationGhanaPigPorcineRotavirus A
原始语种摘要: BACKGROUND(#br)The introduction of rotavirus A vaccination across the developing world has not proved to be as efficacious as first hoped. One cause of vaccine failure may be infection by zoonotic rotaviruses that are very variable antigenically from the vaccine strain. However, there is a lack of genomic information about the circulating rotavirus A strains in farm animals in the developing world that may be a source of infection for humans. We therefore screened farms close to Accra, Ghana for animals sub-clinically infected with rotavirus A and then sequenced the virus found in one of these samples.(#br)RESULTS(#br)6.1% of clinically normal cows and pigs tested were found to be Rotavirus A virus antigen positive in the faeces. A subset of these (33.3%) were also positive for virus RNA....
全文获取路径: PubMed  (合作)
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影响因子:1.861 (2012)

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关键词翻译
关键词翻译
  • rotavirus 轮状病毒
  • asymptomatic 无症状的
  • constellation 星座
  • clinically 临床上
  • developing 显影
  • genomic 染色体组的
  • porcine 猪的
  • therefore 因此
  • vaccination 注射疫苗
  • infection 感染