|作者：||Han Tao, Yang Xiaodan, Xu Ying, Zheng Zhendong, Yan Ying, Wang Ning|
1Department of Oncology.
2Department of Radiotherapy, General Hospital of Shenyang Military Region, Shenyang, China.
|刊名：||OncoTargets and therapy, 2017, Vol.10 , pp.3277-3283|
|关键词：||Brachytherapy; Carcinoma; Iodine isotopes; Liver; Stereotactic techniques;|
|原始语种摘要：||OBJECTIVE(#br)To explore the therapeutic value of 3-D printing template-assisted 125I-seed implantation in the treatment of malignant liver tumors.(#br)MATERIALS AND METHODS(#br)Fifteen liver cancer patients with 47 total lesions were treated with 3-D printing template-assisted radioactive seed implantation (group A), and 25 liver-tumor patients with 66 total lesions were treated with 125I-seed implantation without a template auxiliary (group B). Operation time, in-hospital time, operation complications, dose distribution, and response rate (number) were compared between the two groups.(#br)RESULTS(#br)Shorter operation times and better dose distribution were observed in group A than in group B, and the differences were statistically significant. The response rate... after 2 months was 86.7% (13 of 15) in group A and 84% (21 of 25) in group B; differences between the two groups were not significant.(#br)CONCLUSION(#br)Application of 3-D printing template-assisted radioactive seed implantation in the treatment of malignant liver tumors can help shorten operation time and optimize radiation-dose distribution, is worthy of further study, and has clinical significance.|