Successful treatment of advanced pancreatic liposarcoma with apatinib: A case report and literature review.
作者: Han TaoLuan YutingXu YingYang XiaodanLi JingLiu RanLi QingZheng Zhendong
作者单位: 1a Department of Oncology , Cancer Center of People's Liberation Army, General Hospital of Shenyang, Military Region , Shenyang , P.R. China.
2b Department of Clinical Pharmacy , Shenyang Pharmaceautical University , Shenyang , P.R. China.
3c Department of Radiotherapy , Cancer Center of People's Liberation Army, General Hospital of Shenyang Military Region , Shenyang , P.R. China.
4a Department of O
刊名: Cancer biology & therapy, 2017, Vol.18 (9), pp.635-639
来源数据库: PubMed Journal
DOI: 10.1080/15384047.2017.1345394
关键词: ApatinibLiposarcomaPaclitaxelPancreatic cancerPrognosis
原始语种摘要: Pancreatic liposarcoma is a malignant tumor originated from the pancreas mesenchymal tissue and mostly presented in skin, subcutaneous, periosteum, and long bone on both sides. Both conventional chemotherapy and radiotherapy have limited efficacy and poor prognosis for advanced pancreatic liposarcoma. Here, we reported a case of advanced pancreatic liposarcoma and reviewed the literature specific for liposarcoma of the pancreas and discuss the emerging options of treatment. The patient was treated with apatinib and a cross-line rescue therapy combined with paclitaxel after progressive disease. The therapeutic effect of the combination regimen has been evaluated. Apatinib is an oral tyrosine kinase inhibitor targeting the intracellular domain of vascular endothelial growth factor...
全文获取路径: PubMed  (合作)
影响因子:3.287 (2012)

  • 治疗的 组合
  • liposarcoma 脂肉瘤
  • pancreatic 胰的
  • literature 文献
  • advanced 先进的
  • pancreas 
  • chemotherapy 化学疗法
  • targeting 导向目标
  • treatment 处理
  • combined 组合
  • therapeutic 组合