Prognostic analysis of Chinese patients with metastasis renal cell cancer receiving sorafenib: results from a multicenter long-term follow-up retrospective study.
作者: Guo FangHan TaoLiu ZhaozheSong XishuangZhang QifuKong XiangboLi ChangfuLi ZhenhuaLi ChenggeQu ShuxianZheng ZhendongPiao YingHan YalingXie Xiaodong
作者单位: 1Department of Oncology, Cancer Center of People's Liberation Army, General Hospital of Shenyang Military Region, Shenyang City, People's Republic of China.
2Department of Urology, First Affiliated Hospital of Dalian Medical University, Dalian City, Liaoning Province, People's Republic of China.
3Department of Urology, Jilin Oncology Hospital, China-Japan Union Hospital of Jilin University, Jilin City, Jilin Province, People's Republic of China.
4Department of Urology, China-Japan Union Hospital of Jilin University, Jilin City, Jilin Province, People's Republic of China.
5Department of Urology, Heilongjiang Oncology Hospital, Heilongjiang City, Heilongjiang Province, People's Republic of China.
刊名: OncoTargets and therapy, 2015, Vol.8 , pp.1581-8
来源数据库: PubMed Journal
DOI: 10.2147/OTT.S84994
关键词: PrognosisRenal cell cancerSorafenibTargeted therapy
原始语种摘要: The effects of sorafenib for Chinese patients with metastatic renal cell cancer (mRCC) were evaluated to figure out the relationship between clinical variables and prognosis. The data were analyzed retrospectively from six comprehensive cancer centers in Northeast China. All cases were diagnosed as mRCC histopathologically without exception. Patients were taken 400 mg sorafenib orally twice daily until progression of disease or intolerable toxic reaction occurred. Overall survival (OS), progression-free survival (PFS), and the influence of clinical variables on survival were appointed as main outcome measures. Clinical data were analyzed using SPSS statistical software. P<0.05 was considered as statistically significant. A total of 131 patients were available for survival analysis. The...
全文获取路径: PubMed  (合作)
影响因子:2.073 (2012)

  • metastasis 同质蜕变
  • survival 生存
  • cancer 癌症
  • previous 先前的
  • retrospective 追溯
  • analysis 分析
  • prognosis 预报
  • metastatic 新陈代谢的
  • significantly 较大地
  • prognostic 预测的