Evaluation of the Acute and Sub-chronic Toxic Effects of Aqueous Leaf Extracts of Artemisia afra on Liver, Kidney and Some Blood Parameters in Wistar Rats
作者: Nikodimos Eshetu Mekbeb Afework Eyasu Makonnen Asfaw Debella Wondwossen Ergete Tesfaye Tolesssa
刊名: Advances in Bioscience and Bioengineering, 2016, Vol.4 (1)
来源数据库: Science Publishing Group
DOI: 10.11648/j.abb.20160401.12
关键词: Artemisia afraTraditional MedicineToxicological Assessment
原始语种摘要: Background : Artemisia afra is a plant traditionally used for treatment of different diseases in many parts of the world including Ethiopia. Its effects on different organs, however, have not yet been investigated. The objective of the present study was, therefore, to evaluate the acute and sub-chronic toxic effects of aqueous leaf extracts of Artemisia afra on Liver, Kidney and some Blood parameters in Rats. Methods : For acute toxicity study, aqueous extracts of the leaves were administered in a single dose of 200, 700, 1200, 2200, 3200, 4200 and 5000mg/kg body weight, while the low dose (600mg/kg) and triple of lower dose (1800mg/kg) were used for sub-chronic toxicity studies. Selected hematological and biochemical parameters of the blood followed by histopathological analysis were...
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关键词翻译
关键词翻译
  • toxic 有毒的
  • aqueous 水的
  • treatment 处理
  • chronic 延续很长的
  • hematological 血液学的
  • effects 海员自身物品
  • level 水准
  • higher 
  • leukocytic 白细胞的
  • above 在上面