Protective Efficacy of a Commercial Live Attenuated aroA mutant Vaccine Against Avian Pathogenic Escherichia coli Challenge in Broilers
作者: Ahlam A. Gharib
刊名: Zagazig Veterinary journal, 2017(4)
来源数据库: Pak Publishing Group
DOI: 10.5281/zenodo.1162919
关键词: ChickensAvian pathogenic Escherichia coliAroA mutantVaccine.
原始语种摘要: Avian colibacillosis is an infectious disease of domestic poultry with economic importance. Among the tools available for the control avian pathogenic E. coli (APEC), vaccines have received the most attention. In this research, comparative bacteriological examination between candidates of live aroA mutant E. coli vaccine and two virulent APEC strains (O78 and O125) was carried. Innate immunity (leukogram & Phagocytosis) as well specific cellular (CD4 & CD8) and humoral (agglutinins) immune response of vaccinated chickens were evaluated. Also the mortality rate, colibacillosis lesions and bacterial re-isolation were detected after challenge to stand upon their minimizing in vaccinated chickens. The comparative study demonstrated that the vaccinal and virulent strains were similar in...
全文获取路径: Pak Publishing Group 

  • Escherichia 埃希氏菌属
  • Vaccine 疫苗程序
  • vaccine 菌苗
  • mutant 突变体
  • vaccinal 牛痘的
  • vaccinated 接种疫苗的
  • immune 免疫的
  • humoral 体液的
  • virulent 毒性的
  • heterologous 异种的