The correlation between osteopontin level and radiation response of malignant gliomas at Cipto Mangunkusumo Hospital
作者: Isnaniah Hasan Sri Mutya Sekarutami Renindra A. Aman Nurjati C. Siregar Rahmad Mulyadi
刊名: Advances in Modern Oncology Research, 2016, Vol.2 (6)
来源数据库: PiscoMed Publishing Pte. Ltd
DOI: 10.18282/amor.v2.i6.24
关键词: osteopontinmalignant gliomaradiation response
原始语种摘要: Osteopontin is an endogenous molecular marker for tumor hypoxia, and hypoxia is one of the factors that determine the aggressiveness of the disease. The purpose of this study is to determine the correlation between osteopontin levels and radiation response in malignant glioma. A retrospective cohort study was conducted on 15 malignant glioma patients who underwent radiation therapy from July 2004 to May 2015 at the RSUPN Dr. Cipto Mangunkusumo Hospital. Osteopontin levels were measured from paraffin-embedded tissue using a commercial ELISA kit. Tumor volume was calculated using computed tomography (CT) scan and magnetic resonance imaging (MRI) images, based on three-dimensional volume measurements. Tumor response was evaluated by comparing pre- and post-radiation tumor volumes using CT...
全文获取路径: PiscoMed Publishing  (合作)

  • radiation 辐射
  • correlation 对比
  • malignant 恶性的
  • response 响应
  • glioma 神经胶质瘤
  • level 水准
  • between 在中间
  • hypoxia 氧过少
  • aggressiveness 侵蚀性
  • volume 体积