Antioxidant and Cytotoxic Activity of Water Ethanol Extracts from the Mycelium of Inonotus rheades (Pers.) Bondartsev & Singer
作者: M.K. Borovskaya T.G. Gornostay G.B. Borovskii
刊名: Журнал стресс-физиологии и биохимии, 2016, Vol.12 (4), pp.62-71
来源数据库: Journal of Stress Physiology & Biochemistry
关键词: antioxidant activitycytotoxic activityInonotus rheadesmycelium
原始语种摘要: The important problem of current research is the search for bioactive natural compounds. We have previously demonstrated high in vitro antiradical activity of water ethanol extracts (WEE) from the mycelium species of the genus Inonotus rheades . In the present study we evaluated the effect of 30% and 70% of WEE from mycelium I. rheades on the cell culture of human tumor cells HEp-2. 50% cell death is achieved after incubation in 53 mkg/ml 70% WEE (dry weight), whereas 30% WEE at 550 mkg/ml only, i.e. an order of magnitude difference between the concentrations, which indicates that high cytotoxic activity was shown WEE a radical change in the qualitative composition of extractives with increasing ethanol concentration. Incubation of cells with 250 mM H2O2 resulted in...
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  • cytotoxic 细胞毒素的
  • extracts 摘记
  • incubation 孵化
  • neutralize 使无效
  • concentrations 浓聚物
  • Singer 胜家牌缝纫机
  • effect 效应
  • dilution 稀度
  • ethanol 乙醇
  • oxidative 氧化的