FORMULATION AND IN VITROEVALUATION OF FLOATING TABLETS OF CEFPODOXIME PROXETIL
作者: Bharat W. TekadeUmesh T. JadhaoShruti G. PatilVijay R. Patil
作者单位: 1Department of Pharmaceutics, TVES’s Honorable Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur, (India). bharattekade@yahoo.co.in
刊名: International Journal of Current Pharmaceutical Research, 2017, Vol.9 (6), pp.18-22
来源数据库: Innovare Academics Sciences PVT.Ltd.
DOI: 10.22159/ijcpr.2017v9i6.23422
原始语种摘要: Objective: The objective of research work was to formulate and evaluate the floating drug delivery system containing Cefpodoxime Proxetil using polymer HPMC K4M, Guar Gum.Methods: Effervescent floating tablets containing Cefpodoxime proxetil were prepared by direct compression technique using varying concentrations of different grades of polymer.Results: Physical parameters like hardness, weight variation, thickness and friability were within pharmacopoeial limit. Percentage drug content in all floating tablet formulations was found to be 90% to 110%. The floating time was found to be more than 12 H. floating lag time was found to be 10±2.99 second. Formulation batch F8 was selected as an optimum formulation, as possessing less disintegration time, higher water absorption ratio and good...
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关键词翻译
关键词翻译
  • values 价值观
  • floating 浮动的
  • corresponding 对应的
  • polymer 聚合物
  • batch 一批
  • formulation 配方
  • higher 
  • tablet 药片
  • ratio 
  • found 创立