RECENT NANOCOCHLEATE DRUG DELIVERY SYSTEM FOR CANCER TREATMENT: A REVIEW
作者: SUJIT NAYEKABHIRAMI VENKATACHALAMSANGEETA CHOUDHURY
作者单位: 1Department of Pharmaceutics, Acharya and BM Reddy College of Pharmacy, Soldevanahalli, Hesaraghatta Road, Bangalore 560107, Karnataka, India. sujitnayek29@gmail.com
刊名: International Journal of Current Pharmaceutical Research, 2019, pp.28-32
来源数据库: Innovare Academics Sciences PVT.Ltd.
DOI: 10.22159/ijcpr.2019v11i6.36359
原始语种摘要: Nanocochleates are at the forefront of the fast-growing nanotechnology sector in the delivery of drugs for cancer. This nanotechnology is the use of the cationic and anionic encapsulated drug that has poor oral bioavailability. Nanocochleate is a lipid-based drug delivery in the liposomal vesicles that is converted by calcium divalent cation into nanocochleate. Nanocochleates technology use encapsulations of the anticancer agent, which have low solubility, oral bioavailability and low permeability. This paper shows and provides an overview of the benefits of nanocochleates, drug delivery mechanism, choice of prevalent components (Phospholipids and Cations), various ways of producing nanocochleates and nanocochleate stability. Nanocochleates have far fewer constraints than other...
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关键词翻译
关键词翻译
  • nanotechnology 毫微技术
  • characterize 成为...的特性
  • encapsulated 压缩
  • delivery 移交
  • mechanism 机构
  • producing 产油
  • forefront 最前部
  • overview 概观
  • anionic 阴离子的
  • prevalent 普通