PREFORMULATION STUDIES USING LACTOSE IN DEVELOPMENT OF SOLID ORAL DOSAGE FORM: A GRAPHICAL REPRESENTATION USING SeDeM METHOD
作者: Imran TadweeSadhana ShahiZahed Zaheer
作者单位: 1Y. B. Chavan College of Pharmacy Rouza Buagh, Aurangabad 431001. imran.tpharma@gmail.com
刊名: International Journal of Current Pharmaceutical Research, 2017, Vol.9 (5), pp.168-172
来源数据库: Innovare Academics Sciences PVT.Ltd.
DOI: 10.22159/ijcpr.2017v9i5.22165
原始语种摘要: Objective: The objective of the study is to evaluate and present lactose scientifically as an excipient of choice in formulation development of solid orals dosage form for direct compression method. Present work will establish the ability of lactose as an excipient to be the choice of candidate while developing formulation having poor flow API using direct compression process. In addition to this different type of lactose is processed using secure development method (SeDeM) in order to evaluate best suitable type of lactose amongst its different type.Methods: Lactose anhydrous, lactose monohydrate and Lactose spray dried (SD) were employed for evaluation using SeDeM method, twelve different selected pharmacotechnical parameters were determined experimentally and were treated...
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关键词翻译
关键词翻译
  • lactose 乳糖
  • formulation 配方
  • compression 压缩
  • evaluate 求...的值
  • excipient 赋形剂
  • scientifically 科学上
  • preferred 可取
  • anhydrous 无水的
  • monohydrate 一水化物
  • development 开发