PREPARATION OF ASCORBIC ACID AND CHOLECALCIFEROL MICROSPONGES FOR TOPICAL APPLICATION
作者: Rabia ZiaAkmal NazirMuhammad Kashif Iqbal KhanAbid Aslam MaanAyesha Rashid
作者单位: 1School of Pharmaceutical Sciences, The University of Faisalabad. rabiapharmacist@yahoo.com
刊名: International Journal of Pharmacy and Pharmaceutical Sciences, 2017, Vol.9 (10), pp.280-287
来源数据库: Innovare Academics Sciences PVT.Ltd.
DOI: 10.22159/ijpps.2017v9i10.17525
原始语种摘要: Objective: Apart from having various physiological functions in the body, ascorbic acid (vitamin C) and cholecalciferol (vitamin D3) also have a key role in skin protection. However, their bioavailability is quite limited in the skin, and therefore, many cosmetic products are supplemented with these vitamins, which are usually associated with stability issues. To avoid these issues, here we report on the preparation of microsponges of these vitamins for topical application.Methods: The microsponges were prepared through various emulsification-solvent evaporation methods involving single (O/O, O/W) or double (W/O/O, W/O/W, S/O/W) emulsion. The organic internal phase was consisted of Eudragit® RS 100 polymer dissolved in an organic solvent such as acetone or dichloromethane, at a constant...
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关键词翻译
关键词翻译
  • vitamin 维生素
  • suitable 合适的
  • efficiency 效率
  • appreciable 明显的
  • ACID Aircraft Identification
  • various 千变万化的
  • around 环绕
  • polymer 聚合物
  • constant 常数
  • respectively 分别