EVALUATION OF IN VITRO ANTI-INFLAMMATORY ACTIVITY AND HPTLC ANALYSIS OF PLANT PHYLLANTHUS FRATERNUS
作者: Biresh Kumar SarkarRavi KumarReeta .S. C. VermaShashi PalRamaiah MaddiC. Murali KrishnaRavindra Singh
作者单位: 1Central Ayurveda Research Institute for Respiratory Disorders, (CCRAS, Ministry of AYUSH, Govt. of India) Moti Bagh Road, Patiala, Punjab, India. bireshsarkar@gmail.com
刊名: International Journal of Current Pharmaceutical Research, 2017, Vol.9 (5), pp.198-200
来源数据库: Innovare Academics Sciences PVT.Ltd.
DOI: 10.22159/ijcpr.2017v9i5.22328
原始语种摘要: Objective: The present investigation evaluated in vitro anti-inflammatory activity of Phyllanthus fraternus. Inhibition of Cyclooxygenase and 5-lipoxygenase was performed along with protein denaturation.Methods: Alcoholic extract of plant was subjected to in vitro anti-inflammatory activity and HPTLC analysis.Results: The results of anti-inflammatory activity showed significant inhibition in Cyclooxygenase and 5-lipoxygenase assay, extract also showed more than 70 % inhibition in protein denaturation method. HPTLC of plant materials was also performed; spots of alkaloids were recorded.Conclusion: Different alkaloids were spotted in chromatographic analysis and study suggested that anti-inflammatory activity of Phyllanthus fraternus may be due to the presence of alkaloids.
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关键词翻译
关键词翻译
  • HPTLC 高效薄层色谱法
  • inflammatory 激怒的
  • alkaloids 生物碱类
  • lipoxygenase 脂加氧酶
  • extract 提取
  • protein 蛋白质
  • inhibition 抑制
  • activity 活度
  • denaturation 变性
  • analysis 分析