EVALUATION OF THE WOUND HEALING ACTIVITY OF CAESALPINIA BONDUCELLA AND CYCLEA PELTATA EXTRACTS IN EXPERIMENTALLY INDUCED DIABETIC RATS
作者: Jagadeep Chandra S.Mahadeva Murthy S.Ranjana Ramesh
作者单位: 11Department of Studies in Microbiology, University of Mysore, Manasagangotri, Mysuru 570006, India. Smmurthy2025@gmail.com
刊名: International Journal of Pharmacy and Pharmaceutical Sciences, 2017, Vol.9 (10), pp.211-217
来源数据库: Innovare Academics Sciences PVT.Ltd.
DOI: 10.22159/ijpps.2017v9i10.19788
原始语种摘要: Objective: The present study was conducted to verify the effect of Caesalpinia bonducella and Cyclea peltata extracts on experimentally induced excision wounds in diabetic rats.Methods: Methanolic and ethyl acetate extract of test sample in PEG base was applied and observed for wound healing effect for a period of 15 d.Results: The data demonstrated statistically significant wound contraction up to 98% in the treated sample as compared to 90% in diabetic control group. The results correlated (r ³ 0.95) with fasting blood glucose level, indicating the deleterious effect of hyperglycemia in wound healing. Histopathological studies indicated moderate granulation with marked epithelial enclose and moderate hyperplasia in groups treated with high dose (100 mg/kg BW) of methanolic extract of...
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关键词翻译
关键词翻译
  • 观察到的 
  • diabetic 糖尿病患者
  • extracts 摘记
  • effect 效应
  • granulation 粒化酌
  • phytochemical 植物化学的
  • demonstrated 探明的储量
  • therapeutic 治疗的
  • enclose 
  • observed 
  • hyperglycemia 高血糖