FORMULATION, STABILITY TFORMULATION, STABILITY TEST AND IN VITRO PENETRATION STUDY OF TRANSETHOSOMAL GEL CONTAINING GREEN TEA (CAMELLIA SINENSIS L. KUNTZE) LEAVES EXTRACTEST AND IN VITRO PENETRATION STUDY OF TRANSETHOSOMAL GEL CONTAINING GREEN TEA(CAMELLIA SINENSIS L. KUNTZE) LEAVES EXTRACT
作者: Delly RamadonSeshiana Sebti PramestiEffionora Anwar
作者单位: 1Laboratory of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Indonesia, Depok, West Java, Indonesia. delly.ramadon@farmasi.ui.ac.id
刊名: International Journal of Applied Pharmaceutics, 2017, Vol.9 (5), pp.91-96
来源数据库: Innovare Academics Sciences PVT.Ltd.
DOI: 10.22159/ijap.2017v9i5.20073
原始语种摘要: Objective: The aim of this study was to increase penetration of epigallocatechin gallate (EGCG) from the extract using transethosomal gel.Methods: Transethosomes (TE) formulae were made using thin layer hydration method with different concentration of green tea extract which was equivalent to 1% (F1), 1.5% (F2), and 2% (F3) of EGCG. F1 was the chosen formula to be incorporated into a gel as a transethosomal gel (TEG). A gel containing green tea extract was also made as a control called as non-transethosomal gel (NTEG). A stability test and in vitro penetration study of gels using Franz diffusion cell were performed.Results: F1 was the chosen formula because it had a spherical shape, a particle size of 112.14±2.19 nm, PDI of 0.166±0.03, a zeta potential of-52.05±1.34 mV, and %EE of...
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关键词翻译
关键词翻译
  • extract 提取
  • gallate 没食子酸盐
  • TEA TRANS EUROPEAN AIRWAYS
  • penetration 穿透
  • potential 
  • formula 公式
  • hydration 水合酌
  • concentration 浓度
  • stability 稳定性
  • incorporated 股份有限公司