EVALUATION OF CARDIOPROTECTIVE ACTIVITY OF ALLIUM CEPA AERIAL LEAVES
作者: Jalaiah M.Sarvanan R.Gowtham C. H.Vinay Y.Akhila Y.
作者单位: 1Department of Pharmacology, QIS College of Pharmacy-Ongole, Andhra Pradesh. jali.pharma@gmail.com
刊名: International Journal of Current Pharmaceutical Research, 2017, Vol.9 (6), pp.27-30
来源数据库: Innovare Academics Sciences PVT.Ltd.
DOI: 10.22159/ijcpr.2017v9i6.23424
原始语种摘要: Objective: The present work deals with the study of the ethanolic extract of fruits of Allium cepa aerial leaves for cardioprotective activity.Methods: Cardioprotective activity of the ethanolic extract of aerial leaves of Allium cepa was determined by the administration of isoproterenol (60 mg/kg, s. c) for two days.Results: Pretreatment with ethanolic extract of Allium cepa aerial leaves (200 mg/kg, p. o and 100 mg/kg, p. o) for 28 d in significantly (p<0.01) reduce the levels of serum transaminases, alkaline phosphates, lactate dehydrogenase, creatinine kinase, total cholesterol, triglycerides, LDL-cholesterol, VLDL-cholesterol and increase the levels of HDL-cholesterol. Histopathological studies of the hearts of isoproterenol treated rats have showed infiltration of inflammatory cells...
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关键词翻译
关键词翻译
  • isoproterenol 异丙基肾上腺素
  • cholesterol 胆甾醇
  • extract 提取
  • treated 加工的
  • aerial 天线
  • degenerative 退化的
  • inflammatory 激怒的
  • infiltration 渗透
  • lactate 乳酸盐
  • administration 管理