DEVELOPMENT AND VALIDATION OF A SIMPLE UV SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF SALBUTAMOL SULPHATE FROM PHARMACEUTICAL FORMULATIONS
作者: G. R. GADEKAR S. S PATIL R. R. SHAH D. S. GHODKE
作者单位: 1Department of Pharmaceutics, Appasaheb Birnale College of Pharmacy, South-Shivaji Nagar, Sangli-Miraj Road, Sangli 416416, India. gadekarganesh@gmail.com
刊名: International Journal of Current Pharmaceutical Research, 2019, pp.72-75
来源数据库: Innovare Academics Sciences PVT.Ltd.
DOI: 10.22159/ijcpr.2019v11i5.35707
原始语种摘要: Objective: The present study was undertaken to develop a rapid, simple, specific and economic ultraviolet (UV) spectrophotometric method for estimating the Salbutamol Sulphate (SS) in pharmaceutical formulations. Methods: The analysis was performed at λ max 276 nm using Sorenson’s isotonic phosphate buffer pH 7 (SIPB pH 7) as blank/diluent. The method was validated by following the analytical performance parameters as suggested by International Conference on Harmonization (ICH) which included accuracy, precision, linearity. Results: The drug follows the beer’s lambert’s law in the concentration range of 12.5-37.5μg/ml and exhibited good correlation coefficient (0.9997) and excellent mean recovery. Percentage RSD for precision and accuracy of the method was found to be less than 2%. This...
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关键词翻译
关键词翻译
  • develop 发展
  • claims 赔偿金
  • commercial 商业的
  • successfully 成功地
  • routine 程序
  • precision 精度
  • estimating 价值估计
  • economic 经济的
  • method 方法
  • market 市场