EXPLORATION OF IN VIVO ANTIOXIDANT ACTIVITY OF 50% ETHANOLIC EXTRACT OF SESAMUM INDICUM L. SEED AGAINST HIGH FAT DIET INDUCED RATS
作者: ZAFAR JAVED KHANNAEEM AHMAD KHAN
作者单位: 1Department, of Ilmul Advia, Faculty of Unani Medicine, Aligarh Muslim University, Aligarh. hkmnaeemkhan@gmail.com
刊名: International Journal of Current Pharmaceutical Research, 2019, pp.55-61
来源数据库: Innovare Academics Sciences PVT.Ltd.
DOI: 10.22159/ijcpr.2019v11i6.36342
原始语种摘要: Objective: The aim of the present study was to investigate the in vivo antioxidant potential of 50% ethanolic extract of Sesamum indicum against high-fat diet-induced rats. Methods: Animals were treated with plant extract for 30 d, and a high-fat diet was given to all groups except plain control, throughout, out the study. And alpha-tocopherol acetate (Vit, E) was used as standard. Pre-treatment with 16 mg/100 gm of body weight of 50% ethanolic extract of Sesamum indicum improved the Superoxide dismutase, catalase, glutathione, and lipid peroxidation levels significantly as compared to control group. Results: The present studies revealed that Sesamum indicum has significant in vivo antioxidant activity and can be used to protect tissue from oxidative stress. The result showed that the...
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关键词翻译
关键词翻译
  • significantly 较大地
  • declined 先端下倾的
  • investigate 
  • catalase 过氧化氢酶
  • extract 提取
  • peroxidase 过氧物酶
  • antioxidant 抗氧化剂
  • acetate 醋酸盐
  • improved 改进
  • lipid 脂质