ANTIBACTERIAL AND SYNERGISTIC ACTIVITY OF TERMINALIA CHEBULA AND TERMINALIA BELLERICA FRUIT EXTRACTS AGAINST ESBL PRODUCERS
作者: Bharani ThirunavukkarasuNirmala Purushothaman
作者单位: 1Department of Microbiology, Mohamed Sathak College of Arts and Science, Chennai 600119, Tamilnadu, India. nirmala_dineshkumar@yahoo.com
刊名: International Journal of Current Pharmaceutical Research, 2017, Vol.9 (6), pp.8-11
来源数据库: Innovare Academics Sciences PVT.Ltd.
DOI: 10.22159/ijcpr.2017v9i6.23419
原始语种摘要: Objective: Bacterial infections and the resistance related to indiscriminate antibiotic use have led to an alarming situation in the clinics. The rapid spread of Extended Spectrum Beta Lactamases (ESBLs) and carbapenemase producing Gram negative bacteria has initiated the need for development of a new drug or an alternative choice by using the combination of drugs with medicinal plant extracts. This study was aimed at examining the antibacterial potential and synergistic activity of ethanolic extracts of Terminalia chebula and Terminalia bellerica fruits against clinically important reference bacterial strains.Methods: The crude ethanolic extracts of T. chebula and T. bellerica fruits were prepared and reconstituted with 5% dimethylsulfoxide (DMSO). The fruit extracts (~25 mg/well) were...
全文获取路径: IAS  (合作)
分享到:

×
关键词翻译
关键词翻译
  • cefotaxime 头孢噻肟
  • ceftazidime 头孢噻甲羧肟
  • extracts 摘记
  • antibiotic 抗生素
  • bacteria 细菌
  • synergistic 协同的
  • antibacterial 抗细菌的
  • activity 活度
  • combination 聚形
  • indiscriminate 无差别的