A PERSPECTIVE REVIEW ON APPLICATIONS OF NANOPARTICLE MEDIATED DRUG DELIVERY TO THE CNS
作者: V. KEERTHANAS. DHANALAKSHMIN. HARIKRISHNAN
作者单位: 1Pharma Buddy, Faculty of Pharmacy, Dr. M. G. R Educational and Research Institute, Velappanchavadi, Chennai 600077. keerthuvijay10@gmail.com
刊名: International Journal of Current Pharmaceutical Research, 2020, pp.1-4
来源数据库: Innovare Academics Sciences PVT.Ltd.
DOI: 10.22159/ijcpr.2020v12i1.36819
原始语种摘要: Delivery of drugs into the brain is one of the most interesting and challenging areas of research. The blood-brain barrier (BBB) is a highly selective semipermeable membrane that separates blood from the brain in the central nervous system. It acts as a barrier to protect the brain from microbes, neurotoxins and other chemical substances and also blocks the entry of many drugs into the brain. An estimated 6.8 billion people die every year from CNS diseases like Parkinson’s disease, Alzheimer’s disease, sclerosis, brain stroke, dementia and others. According to WHO, one billion people are affected worldwide, about 50 million suffer from epilepsy and 24 million suffer from Alzheimer and other dementias. This indicates the importance of the delivery of drugs into the brain for treating...
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关键词翻译
关键词翻译
  • barrier 堡坝
  • CNS Communications Network Simulator
  • people 民族
  • drugs 药品
  • importance 重要性
  • brain 
  • tremendous 极大的
  • system 
  • designing 设计
  • about 大约