The Stability Study of a Novel Phenylpiperazine Derivative
作者: Monika TARSA Małgorzata STAREK Monika DĄBROWSKA Marzena BARAN Agnieszka CZARNY Marek CEGŁA
刊名: Modern Organic Chemistry Research, 2019, Vol.4 (1)
来源数据库: Isaac Scientific Publishing
关键词: N-phenylpiperazineStabilitySpectrophotometryChromatography
原始语种摘要: N-phenylpiperazine compounds are a very large class of chemicals, and some of them have the ability to cross the blood-brain barrier due to the small size and the lipohilic nature. This group of compounds shows an interesting spectrum of biological activities. The chemical stability of the drugs determines the quality of the drug, affects safety, efficacy and storage conditions. The active compounds have diverse molecular structure and are susceptible to many variable degradation pathways, such as hydrolysis, oxidation, photodegradation, isomerization, elimination, dehydration and interaction with others substances. A hydrolysis degradation process is one of the most common destructive processes for chemical structures. It depends on various conditions e.g. temperature, pH and the...
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  • chemical 化学的
  • degradation 减嚣夷酌
  • oxidation 氧化
  • conditions 条件式
  • biological 生物学的
  • compounds 化合物
  • elimination 排出
  • quality 品质
  • various 千变万化的
  • hydrolysis 水解