Psoriatic arthritis
作者: Vanessa Ocampo DDafna Gladman
作者单位: 1University of Toronto, Psoriatic Arthritis Program, University Health Network, Toronto Western Hospital, Toronto, Ontario, Canada
2Krembil Research Institute, Toronto Western Hospital, Toronto, Ontario, Canada
刊名: F1000Research, 2019, Vol.8
来源数据库: F1000 Research Ltd
DOI: 10.12688/f1000research.19144.1
关键词: Psoriatic arthritisPathogenesisTreatmentBiomarkers
原始语种摘要: Psoriasis is a multisystemic, inflammatory skin condition that can affect many areas of the body, but most commonly the extensor surfaces of the elbows and knees, and sometimes the intergluteal and umbilical area. It has a prevalence of 2–4% in western adults, and 20­–30% of psoriasis patients will develop psoriatic arthritis (PsA). PsA is an inflammatory musculoskeletal disease associated with cutaneous psoriasis. It affects men and women almost equally with a peak age at onset of 40 and 50 years. It is a diverse disease that affects multiple organ systems includes peripheral and axial joints, entheses, skin, and nails. PsA is associated with comorbidities such as osteoporosis, uveitis, subclinical bowel inflammation, and cardiovascular disease. Given this heterogeneity, its diagnosis...
全文获取路径: F1000 Research Ltd 

  • arthritis 关节炎
  • psoriasis 干癣
  • psoriatic 牛皮癣的
  • osteoporosis 骨质疏松
  • umbilical 供应脐带
  • therapeutic 治疗的
  • biologic 生物
  • extensor 伸肌
  • findings 结论
  • subclinical 亚临床的