Pulmonary Fibrosis Due to Nitrofurantoin Therapy: A Case Report
作者: Leonidas GrigorakosGaryphallia PoulakouDaria LazarescuPavlos MyrianthefsNikolaos MarkouMaria BikouAdamantia PetineliKonstantinos Kokkinis
作者单位: 1Faculty of Nursing, National and Kapodistrian University of Athens, Athens, Greece
2Intensive Care, “KAT” Trauma Hospital of Athens, Athens, Greece
3Fourth Department of Internal Medicine, Infectious Disease Unit, Attikon University General Hospital of Athens, Athens, Greece
4Radiology Department, “KAT” Trauma Hospital of Athens, Athens, Greece
刊名: Open Journal of Respiratory Diseases, 2017, Vol.7 (3), pp.117-124
来源数据库: Scientific Research Publishing Journal
DOI: 10.4236/ojrd.2017.73012
原始语种摘要: We report the case of a patient with pulmonary fibrosis, developed as an adverse reaction to nitrofurantoin therapy received for totally 6 months for the prevention of recurrent urinary tract infections. Chest X-ray and CT scan revealed extensive elements of interstitial pulmonary fibrosis. After diagnosis, administration of nitrofurantoin was immediately stopped; and specific prolonged therapy with low-dose corticosteroids per os and inhaled steroids were administered. The patient responded successfully both clinically and biochemically and possible digestive system side effects were prevented through the administration of gastroprotection medication. For the prevention of urinary tract infection, the patient received well tolerated therapy with fosfomycin which was further continued as...
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  • nitrofurantoin 硝化呋喃托英
  • fosfomycin 磷霉素
  • fibrosis 纤维化
  • urinary 尿的
  • prevention 妨碍
  • administration 管理
  • prophylactic 预防性的
  • pulmonary 肺的
  • received 接收
  • infection 感染