Broken flow symmetry explains the dynamics of small particles in deterministic lateral displacement arrays
刊名: Proceedings of the National Academy of Sciences of the United States of America, 2017, Vol.114 (26), pp.E5034-E5041
来源数据库: JSTOR
关键词: NanofluidicsDeterministic ratchetParticle tracking
原始语种摘要: Deterministic lateral displacement (DLD) is a technique for size fractionation of particles in continuous flow that has shown great potential for biological applications. Several theoretical models have been proposed, but experimental evidence has demonstrated that a rich class of intermediate migration behavior exists, which is not predicted. We present a unified theoretical framework to infer the path of particles in the whole array on the basis of trajectories in a unit cell. This framework explains many of the unexpected particle trajectories reported and can be used to design arrays for even nanoscale particle fractionation. We performed experiments that verify these predictions and used our model to develop a condenser array that achieves full particle separation with a single...
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关键词翻译
关键词翻译
  • deterministic 确定性
  • ratchet 棘轮
  • unexpected 突然的
  • lateral 侧面的
  • develop 发展
  • displacement 迁移
  • particle 颗粒
  • evidence 
  • great 大的
  • fractionation 分级