Second-line Drug Resistance Characterization in Mycobacterium tuberculosis by Genotype MTBDRsl Assay
作者: Sunil SethiPriyanka AgarwalRajiv KhanejaNaresh KumarNitin KumarJagesh ChandnaAshutosh N. AggarwalRakesh Yadav
刊名: Journal of Epidemiology and Global Health, 2020
来源数据库: Atlantis Press
DOI: 10.2991/jegh.k.191215.003
原始语种摘要: Tuberculosis (TB) remains a main hurdle for national programs due to increase in drug resistance to antitubercular drugs. World Health Organization (WHO)-endorsed Line Probe Assay, Genotype MTBDRsl Ver 2.0, gives opportunity for rapid diagnosis and molecular characterization of different mutations in drug targets of fluoroquinolone (FQ) and second-line injectable drugs (SLID). We, retrospectively, analyzed the data of Genotype MTBDRsl Ver 2.0 from January 2018 to June 2018. A total of 863 isolates of Mycobacterium tuberculosis, 687 rifampicin resistant and 176 isoniazid resistant only, were screened for drug resistance in FQ and SLID. All the isolates were tested for Genotype MTBDRsl Ver 2.0 according to the manufacturer’s instructions. The FQ and SLID resistance were detected in 295...
全文获取路径: Atlantis出版社 

  • Mycobacterium -ria
  • tuberculosis 肺结核
  • isolates 单离体
  • resistant 耐久的
  • antitubercular 抗结核的
  • programmatic 纲领性的
  • resistance 抵抗
  • opportunity 机会
  • injectable 可注射的
  • second