Improvement of Bone Filler Materials Using Granular Calcium Sulfate Dihydrate-Gelatin-Polycaprolactone Composite
作者: Difa Putri UtamiSunarso SunarsoYosi Kusuma EriwatiSiti TriaminingsihDecky Joesiana IndraniDessy Innawaty
作者单位: 1Universitas Indonesia
刊名: Key Engineering Materials, 2020, Vol.4790 , pp.63-68
来源数据库: Trans Tech Journal
DOI: 10.4028/
关键词: Bone FillerPolycaprolactoneGranularGelatinCompositeCalcium Sulfate Dihydrate
原始语种摘要: Calcium sulfate dihydrate (CSD) cement has been used as bone void filler and antibiotic carrier for many years. However, the main drawback of CSD cement is its brittleness that limits its handling property. Thus, the aim of this study is to fabricate granular CSD cement-gelatin-polycaprolactone (CSD-Gel-PCL) to improve handling property. To prepare CSD-Gel-PCL composite, granular CSD was prepared from calcium sulfate hemihydrate (CaSO4.0.5H2O; CSH) and distilled water with water/powder (W/P) ratio of 0.5. The CSD cement was crushed and sieved into 300-500 μm. The obtained granular CSD was then mixed with 3 wt.%, 5 wt.% and 7 wt.% gelatin solution which previously mixed with PCL (50 wt% PCL, 50 wt% gelatin), followed by freeze drying for 48 hours. The CSD granules...
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  • granules 粒剂
  • granular 粒状的
  • gelatin 
  • sulfate 硫酸盐
  • cement 胶结物
  • suggested 建议
  • PCL Packet Control Layer
  • CSD Circuit Switched Data
  • higher 
  • ratio