Study on the Contact Stress Concentration and the Hyperplasia of the Canine Trachea Granulation Tissue after Stenting
作者: Zhiguo Zhang, Ming Zhu, Xiaowei Yu, Xiaohao Shi, Chen Jiang, Yimin Sun, Ming Zhang, Yue Wang, Yuqiao Wen and Chingcheng Huang
刊名: MCB: Molecular & Cellular Biomechanics, 2018, Vol.15 (1), pp.51-61
来源数据库: Tech Science Press
DOI: 10.3970/mcb.2018.015.051
关键词: Tracheal restenosisTrachea granulation tissueContact stress concentration“Stress-growth” relationship3D numerical model.
原始语种摘要: Tracheal stenosis is a common respiratory disease and is usually treated by stent implantation. However, the implanted stent often causes excessive hyperplasia of trachea granulation tissue, leading to the restenosis. Although surgical removal or chemical suppression can be used to alleviate the restenosis, the efficacy is limited. Thus, restenosis remains a thorny complication. We investigated this issue from the perspective of the “tress-growth”relationship. Firstly, the lower airway of 5 experimental dogs were CT-scanned to reconstruct the 3D numerical models; secondly, the implantations of the Nitinol alloy stents were numerically simulated; thirdly, 45 days after the stenting, the dogs were evaluated for the hyperplasia of the trachea granulation tissue by CT imaging, bronchoscopy...
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  • 化学的 浓度
  • granulation 粒化酌
  • relationship 关系
  • restenosis 再狭窄
  • removal 消去
  • hyperplasia 增生
  • positively 断然
  • concentration 浓度
  • chemical 浓度
  • growth 生长
  • tissue 组织