Multiple antibiotic resistance (MAR) index and its reversion in Pseudomonas aeruginosa
作者: S. PaulR. L. BezbaruahM. K. RoyA. C. Ghosh
作者单位: 1Division of Biochemistry, Regional Research Laboratory, Jorhat, Assam, India
刊名: Letters in Applied Microbiology, 1997, Vol.24 (3), pp.169-171
来源数据库: Wiley Journal
DOI: 10.1046/j.1472-765X.1997.00364.x
原始语种摘要: The MAR indexes of hospital isolates of Pseudomonas aeruginosa were determined with reference to nine different cephalosporins. The values for all the strains were higher than 0·2 suggesting their origin from a high risk source of contamination where antibiotics are often used. Emergence of MAR pathogenic strains of Ps. aeruginosa indicated possible nosocomial infection in the hospital environment. β‐Lactamases produced by these organisms were tested and their inhibition by clavulanic acid was studied. β‐Lactamase produced by one of these strains (Ps‐1) could not be inhibited by clavulanic acid whereas β‐lactamases of three other strains (Ps‐2, Ps‐3 and Ps‐4) could be inhibited by clavulanic acid in the presence of cephalosporins, suggesting a possible use of clavulanic acid in...
全文获取路径: Wiley  (合作)

  • antibiotic 抗生素
  • MAR Machine-Aided Retrieval
  • cephalosporins 头孢菌素类
  • nosocomial 医院的
  • reversion 返祖
  • induced 感应的
  • lactamase 内酰胺酶
  • inhibited 被禁止
  • resistance 抵抗
  • produced 出品