Total Synthesis of Ceratopicanol through Tandem Cycloaddition Reaction of a Linear Substrate
作者: Sang‐Shin LeeWon‐Yeob KimProf. Dr. Hee‐Yoon Lee
作者单位: 1Department of Chemistry, KAIST, 373‐1 Gusung Dong, Yuseong, Daejeon, 305‐701 (Korea), Fax: (+82) 42‐350‐2810
2 Department of Chemistry, KAIST, 373‐1 Gusung Dong, Yuseong, Daejeon, 305‐701 (Korea), Fax: (+82) 42‐350‐2810
刊名: Chemistry – An Asian Journal, 2012, Vol.7 (10), pp.2450-2456
来源数据库: Wiley Journal
DOI: 10.1002/asia.201200497
关键词: diradicalcycladdition reactionstereoselectivitytotal synthesistriquinane
原始语种摘要: Abstract(#br)Total synthesis of ceratopicanol ( 1 ) was achieved with a tandem cycloaddition reaction of allenyl diazo compound 6 via a trimethylenemethane (TMM) diyl intermediate. The TMM diyl mediated [2+3] cycloaddition reaction furnished the consecutive quaternary carbon centers and showed an unusual diastereoselectivity.
全文获取路径: Wiley  (合作)
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关键词翻译
关键词翻译
  • cycloaddition 环加
  • diradical 双游离基
  • reaction 反酌
  • Substrate 感光胶层、基片
  • diazo 重氮
  • synthesis 合成
  • centers 机组间距
  • compound 复合物
  • tandem 串联机
  • achieved 获得的