Psychotropic drugs and the risk of fall injuries, hospitalisations and mortality among older adults
作者: Kristina JohnellGudrun Jonasdottir BergmanJohan FastbomBengt DanielssonNatalia BorgPeter Salmi
作者单位: 1Aging Research Center, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society Karolinska Institutet and Stockholm University Stockholm Sweden
2 The Swedish National Board of Health and Welfare (Socialstyrelsen) Stockholm Sweden
刊名: International Journal of Geriatric Psychiatry, 2017, Vol.32 (4), pp.414-420
来源数据库: Wiley Journal
DOI: 10.1002/gps.4483
关键词: ageddementiapsychotropic drugsSweden
原始语种摘要: Objective(#br)To investigate whether psychotropics are associated with an increased risk of fall injuries, hospitalizations, and mortality in a large general population of older adults.(#br)Methods(#br)We performed a nationwide matched (age, sex, and case event day) case–control study between 1 January and 31 December 2011 based on several Swedish registers (n = 1,288,875 persons aged ≥65 years). We used multivariate conditional logistic regression adjusted for education, number of inpatient days, Charlson co‐morbidity index, dementia and number of other drugs.(#br)Results(#br)Antidepressants were the psychotropic most strongly related to fall injuries (ORadjusted: 1.42; 95% CI: 1.38–1.45) and antipsychotics to hospitalizations (ORadjusted: 1.22; 95% CI: 1.19–1.24)...
全文获取路径: Wiley  (合作)

  • psychotropic 精神药品
  • older 
  • mortality 死亡率
  • drugs 药品
  • dementia 痴呆
  • inpatient 住院病人
  • nationwide 全国
  • antipsychotics 抗精神病药
  • death 
  • multivariate 多元