Bone grafts as carriers for local antibiotic delivery for the treatment and prevention of bone infections.
作者: Fani LalidouGeorge KoliosAnna TavridouGeorgios I Drosos
作者单位: 1Medical School, Democritus University of Thrace Alexandroupolis, Greece.
2Laboratory of Pharmacology Medical School, Democritus University of Thrace Alexandroupolis, Greece.
刊名: Surgical technology international, 2014, Vol.25
来源数据库: Surgical Technology Online
原始语种摘要: Osteomyelitis is a bone infection accompanied by inflammatory process, which can lead to destruction and bone necrosis. It is difficult to manage, and there are no commonly accepted guidelines. While most acute bone infections are usually successfully treated with intravenous antibiotics, chronic infections and infections in the presence of foreign materials usually require operative treatment with debridement, removal of metals, intravenous antibiotics, and very often local antibiotics. The aim of this study was to perform a systematic review of the existing literature concerning the use of bone grafts as carriers for local antibiotic delivery for the treatment and prevention of bone infections. According to the literature, antibiotic-loaded autologous bone grafts for the treatment of...
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关键词翻译
关键词翻译
  • antibiotic 抗生素
  • prevention 妨碍
  • treatment 处理
  • delivery 移交
  • loaded 加负荷的
  • nonunion 未加入工会
  • literature 文献
  • local 局部的
  • debridement 清创术
  • arthroplasty 关节成形术