Formulation and Characterization of Repaglinide Chitosan Nanoparticles for the Treatment of Diabetes Mellitus Type II
作者: Nidhi GautamAshwani Mishra
作者单位: 1Department of Pharmacy, Barkatullah University, Bhopal (M.P.)-462026. bdgnidhi@yahoo.co.in
刊名: Current Research in Pharmaceutical Sciences, 2019, pp.270-277
来源数据库: Empro Publications
原始语种摘要: The aim of this study was to prepare and characterize the nanoparticle formulation of Repaglinide to facilitate the development of a novel drug delivery system with improved efficacy and bioavailability. These particles were prepared by Ionotropic gelation method. Prepared formulations were evaluated for Zeta potential, Particle size Polydispersibility index, entrapment efficiency, production yield and in vitro drug release. The formulation batch F4 was found to be best formulation among all the prepared formulations because it showed least particle size, better poly dispersibility index, entrapment efficiency and in vitro drug release.
全文获取路径: Empro出版社  (合作)
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关键词翻译
关键词翻译
  • nanoparticle 乳酸
  • dispersibility 分散性
  • prepare 准备
  • characterize 成为...的特性
  • formulation 配方
  • improved 改进
  • entrapment 诱陷
  • gelation 软胶化
  • batch 一批
  • efficiency 效率