Evaluation of antinociceptive effect of methanolic leaf and root extracts of Clitoria ternatea Linn. in rats
作者: Linggam KamillaSurash RamanathanSreenivasan SasidharanSharif Mansor
作者单位: 1Center for Drug Research, Universiti Sains Malaysia, Penang
2Institute for Research in Molecular Medicine, Universiti Sains Malaysia, Penang
刊名: Indian Journal of Pharmacology, 2014, Vol.46 (5), pp.515-520
来源数据库: Wolters Kluwer Journal
DOI: 10.4103/0253-7613.140583
关键词: Anti-inflammatoryantinociceptiveC. ternateaopioid receptors
原始语种摘要: Aim: Clitoria ternatea Linn. (C. ternatea) is an Ayurvedic herb traditionally used as medicine to relieve inflammatory, rheumatism, ear diseases, fever, arthritis, eye ailments, sore throat and body ache. This study aims to evaluate and elucidate the possible mechanism underlying the antinociceptive action of methanolic extracts of C. ternatea leaf and root using several antinociception models. Materials and Methods: The different antinociception models such as hot plate, tail-flick and formalin tests were used along with naloxone (a non-selective opioid antagonist) to establish the antinociceptive activity of both leaf and root extracts. Results: Both C. ternatea leaf and root extracts markedly demonstrated antinociceptive action in experimental animals. Results of formalin test showed...
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影响因子:0.583 (2012)

  • extracts 摘记
  • supraspinal 刺突上的
  • effect 效应
  • analgesics 镇痛药
  • flick 绒毛
  • opioid 鸦片样物质
  • naloxone 纳洛酮
  • rheumatism 风湿病
  • activity 活度
  • arthritis 关节炎