Outcomes of patients with stroke treated with thrombolysis according to prestroke Rankin Scale scores
作者: Christoph GumbingerPeter RinglebFranziska IppenMatthias UngererBjörn ReuterIngo BruderMichael DaffertshoferChristian Stock
作者单位: 1From the Department of Neurology (C.G., P.R., F.I., M.U.) and Institute of Medical Biometry and Informatics (C.S.), University of Heidelberg; Department of Neurology and Geriatrics (B.R.), Helios Klinik Muellheim; Quality Assurance in Health Care Ltd (QiG BW GmbH) (I.B.), Stuttgart; Department of Neurology (M.D.), Klinikum Mittelbaden Rastatt-Forbach; and Stroke Working Group of Baden-Württemberg (P.R., M.D.), Germany.
刊名: Neurology, 2019
来源数据库: Wolters Kluwer Journal
DOI: 10.1212/WNL.0000000000008468
原始语种摘要: BACKGROUND: It is common practice to withhold IV thrombolysis (IVT) for acute ischemic stroke in patients with preexisting disabilities. To test the hypothesis of an association of IVT and good clinical outcome also in patients with preexisting disabilities without an increase in mortality, we analyzed data from 52,741 patients (15,317 treated with IVT) depending on prestroke Rankin Scale (pRS) score. METHODS: We performed an observational study based on a consecutive stroke registry covering 10.8 million inhabitants. The outcome at discharge of patients with stroke admitted in the time window of potential eligibility for IVT (<4.5 hours after stroke onset) was compared between patients treated and those not treated with thrombolysis, stratified by pRS score. Logistic regression analysis...
全文获取路径: Wolters Kluwer 
影响因子:8.249 (2012)

  • score 得分
  • thrombolysis 血栓溶解
  • according 按照
  • treated 加工的
  • justified 两端
  • estimate 估计
  • evidence 
  • practice 实践
  • potential 
  • between 在中间