Evaluation of 18F-FDG PET/CT parameters for reflection of aggressiveness and prediction of prognosis in early-stage cervical cancer
作者: Le ZhangHongzan SunSiyao DuWeina XuJun XinQiyong Guo
作者单位: 1Department of Radiology
2Department of Nuclear Medicine, Shengjing Hospital of China Medical University
刊名: Nuclear Medicine Communications, 2018
来源数据库: Wolters Kluwer Journal
DOI: 10.1097/MNM.0000000000000909
原始语种摘要: PURPOSE: The aim of this study was to investigate the value of five typical fluorine-18-fluorodeoxyglucose PET/computed tomography (CT) parameters (including SUVmax, SUVmean, SUVpeak, MTV and TLG) in the reflecting aggressiveness and predicting prognosis in patients with early-stage cervical cancer. PATIENTS AND METHODS: Our study enrolled 85 primary cervical cancer patients who underwent preoperative fluorine-18-fluorodeoxyglucose PET/CT scans. We investigated the association of five parameters derived from PET/CT with clinicopathological characteristics. Immunohistochemistry was utilized to evaluate the expression of glucose transporter protein-1 (GLUT-1), TP53-induced glycolysis and apoptosis regulator (TIGAR), and vascular endothelial growth factor (VEGF), and the correlation between...
全文获取路径: Wolters Kluwer 
影响因子:1.379 (2012)

  • cervical 颈的
  • prognosis 预报
  • aggressiveness 侵蚀性
  • PET PagE frame Table
  • stage 
  • parameters 参数
  • cancer 癌症
  • survival 生存
  • preoperative 操作前的
  • early