The novel biomarkers in diagnosis of prostate cancer
作者: Qi Liu1# Jianjun Ding2# Yifei Liu2 Zhenzuo Jiang2 Lin Li3 Bingxin Xiao2 Zhenjie Wang4 *
刊名: Cancer+, 2019, Vol.1 (1)
来源数据库: Whioce Publishing Pte. Ltd
DOI: 10.18063/c+.v1i1.233
关键词: Prostate cancerBiomarkerClinical diagnosis
原始语种摘要: The prostate specific antigen (PSA) as a biomarker for prostate cancer (PCa) diagnosis has been widely used in the clinic for several decades. However, PSA has a low specificity for PCa diagnosis, thereby several gene, blood and urine-based biomarkers (such as sarcosine) underlying biology of PCa progression are being developed to improve the accuracy of PCa diagnosis. In the present review, we focus on novel PCa biomarkers, which are ptentially superior to PSA in PCa screening and facilitate clinical PCa diagonosis. The early PCa screening with reliable biomarkers is critical in reducing the mortality of clinical PCa (high-risk PCa). For clinical insignificant PCa (low-risk PCa) patients and benign prostatic hyperplasia patients, biopsies should be avoided and disease progression should...
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关键词翻译
关键词翻译
  • prostate 前列腺
  • diagnosis 特镇述
  • PSA 被保护的存储器地址
  • novel 长篇小说
  • cancer 癌症
  • prostatic 前列腺的
  • hyperplasia 增生
  • clinic 诊疗所
  • superior 优秀的
  • sarcosine 肌氨酸