Research progress of ferroptosis and urinary tumors
作者: BB Xiong JS Zhang HF Wang YG Zuo JS Wang
刊名: Cancer+, 2019, Vol.1 (2)
来源数据库: Whioce Publishing Pte. Ltd
DOI: doi: 10.18063/c+.v1i2.204
关键词: FerroptosisIron-dependent cell deathUrinary tumorsTumorous diseasesErastin
原始语种摘要: Since the researchers discovered ferroptosis in 2012, they have conducted in-depth research and exploration on the mechanism of ferroptosis and its role in tumor evolution. ferroptosis is a new type of death that is different from apoptosis and necrosis. It is mainly dependent on the cell death caused by the increase of iron and lipid oxygen in the cell and the imbalance of redox homeostasis. After the development of urinary tumors in the middle and late stage, most patients have poor surgical results. Chemotherapy is usually given after surgery. However, some tumor cells are currently resistant to chemotherapy drugs. Therefore, the occurrence of ferroptosis increases a new idea in the treatment of urinary tumors. The purpose of this review is to outline the knowledge of ferroptosis...
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  • progress 发展
  • urinary 尿的
  • development 开发
  • purpose 目的
  • provide 规定
  • given 已知的
  • dependent 从属的
  • chemotherapy 化学疗法
  • mainly 主要地
  • treatment 处理