Bioprinting of osteochondral tissues: A perspective on current gaps and future trends
作者: Pallab Datta Aman Dhawan Yin Yu Dan Hayes Hemanth Gudapati Ibrahim T. Ozbolat
刊名: International Journal of Bioprinting, 2017, Vol.3 (2)
来源数据库: Whioce Publishing Pte. Ltd
DOI: 10.18063/IJB.2017.02.007
关键词: bioprintingosteochondral injurieszonal anisotropybioinktissue engineering
原始语种摘要: Osteochondral tissue regeneration has remained a critical challenge in orthopaedic surgery, especially due to complications of arthritic degeneration arising out of mechanical dislocations of joints. The common gold standard of autografting has several limitations in presenting tissue engineering strategies to solve the unmet clinical need. However, due to the complexity of joint anatomy, and tissue heterogeneity at the interface, the conventional tissue engineering strategies have certain limitations. The advent of bioprinting has now provided new opportunities for osteochondral tissue engineering. Bioprinting can uniquely mimic the heterogeneous cellular composition and anisotropic extra-cellular matrix (ECM) organization, while allowing for targeted gene delivery to achieve heterotypic...
全文获取路径: Whioce Publishing  (合作)
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关键词翻译
关键词翻译
  • orthopaedic 矫形术的
  • joint 节理
  • autografting 人自体组织移植术
  • engineering 工程
  • perspective 透视画法
  • limitations 局限性
  • tissue 组织
  • heterotypic 异型的
  • current 
  • clinical 临床的