The identification and classification of endogenous retroviruses in the horse genome
作者: Batmagnai EErik Bongcam-RudloffMatthew Peter KentGöran Andersson
刊名: Mongolian Journal of Agricultural Sciences, 2018, Vol.23 (01), pp.3-8
来源数据库: Mongolia journals online
DOI: 10.5564/mjas.v23i01.1012
原始语种摘要: Endogenous retroviruses (ervs) are sequences that derived from ancient retroviral infections of germ cells and integrated in humans, mammals and other vertebrates millions years ago. These ervs are inherited according to Mendelian expectations as all other genes in the genome. Coding sequences are flanked by two ltrs (long terminal repeat sequences). Most ervs are defective however some ervs still have open reading frames in their genome. These ervs settle close to functional genes or within the genes and can influence or control functions of the host genes using their ltrs. Most integration has deleterious effects. However some integration could be example of positive co-adaptation as syncitin. The first equine endogenous beta retrovirus which is ecerv-beta1 has been found in 2011 by...
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  • genome 基因组
  • endogenous 内成的
  • horse 夹石
  • retrovirus 还原病毒
  • region 地域
  • amplified verification扩大核查
  • functional 功能的
  • equine 马的
  • upstream 向上游
  • integration 集成