Comparison and correlation study of polar biomarkers of CKD patients in saliva and serum by UPLC-ESI-MS
作者: Jielian yanLi ZhouXiaohong TangYong LiuXiaohong TangYong LiuYixiang Duan
作者单位: 1Research Center of Analytical Instrumentation, Analytical & Testing Center, Sichuan University, Chengdu, Sichuan,610064, China
2Department of Nephrology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610064, China
3Research Center of Analytical Instrumentation, Key Laboratory of Bio-resource and Eco-environment, Ministry of Education, College of Life Science, Sichuan University, Chengdu, Sichuan, 610064, China
刊名: Journal of Advances in Medicine Science, 2019, Vol.2 (3)
来源数据库: Bilingual Publishing Co.
DOI: 10.30564/jams.v2i3.640
原始语种摘要: Abstract:There are abundant reports on the use of aromatic amino acids and creatinineas biomarkers in serum and urine forCKD(chronic kidney disease). However, investigationsinto these bio-species in bio-fluids, such as saliva and sweat, are rarely reported. Increasing interest in non-invasive methods for medical diagnosis advocates for the testing of these bio-fluidstoidentify potential biomarkers for prompt clinical andpreliminary screening using advanced analytical equipment.Unstimulated whole saliva samples were obtained from twenty-seven CKD patients and an equivalent number of healthy individuals. Saliva was assayed with ultra-performance liquid chromatography coupled with electro-spray ionization tandem mass spectrometry (UPLC-ESI-MS) in hydrophilic interaction chromatography mode....
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关键词翻译
关键词翻译
  • saliva 唾液
  • CKD ChecKing Operator
  • serum 血清
  • abundant 丰富的
  • screening 筛分
  • demonstrated 探明的储量
  • potential 
  • several 各自
  • evaluate 求...的值
  • twenty 二十