Exploring Existence of Host-Guest Inclusion Complex of β-Cyclodextrin of a Biologically Active Compound with the Manifestation of Diverse Interactions
作者: Habibur RahamanNiloy RoyAditi RoySamapika RayMahendra Nath Roy
刊名: Emerging Science Journal, 2018, Vol.2 (5)
来源数据库: Ital Publication
DOI: 10.28991/esj-2018-01149
关键词: Β-Cyclodextrin (Β-CD)Para Nitro-Benzaldehyde (PNB)Inclusion Complex (IC)Scanning Electron Microscope (SEM)
原始语种摘要: The host–guest interaction of p-nitro benzaldehyde as guest β-Cyclodextrins have been investigated which have significant applications in the field of medicine such as controlled drug delivery. The 1H NMR study confirms the formation of inclusion complex while surface tension and conductivity studies support the formation inclusion complex with 1:1 stoichiometry. The stoichiometry of the inclusion complex was also supported with Job’s plot method by UV-Visible spectroscopy. FT-IR spectra and SEM study also support the inclusion process. Association constants of the inclusion complexes have been calculated using the Benesi–Hildebrand method, while the thermodynamic parameters have been estimated with the help of van’t Hoff equation.
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  • Electron 埃雷克特龙镁合金
  • complex 超群
  • guest 客户
  • stoichiometry 化学计量学
  • parameters 参数
  • inclusion 包体
  • formation 建造
  • calculated 计算的
  • study 学习
  • estimated 估计的