Peg-based temperature sensitive nanoparticle synthesis and their use in protein adsorption
作者: Guldem Utkan
刊名: Archive of Biomedical Science and Engineering, 2018, Vol.4 (1), pp.021-024
来源数据库: Peertechz Publications Private Limited
DOI: 10.17352/abse.000010
原始语种摘要: In this study, temperature sensitive polymeric nanoparticles were prepared by emulsifier free emulsion polymerization. N-isopropylacrylamide (NIPA) has been used as main monomer to give temperature sensitivity and poly(ethyleneglycol) ethyl ether methacrylate (PEG-EEM) has been added to recipes as comonomer to aid in particle formation. The effect of NIPA, PEG-EEM and crosslinker content on particle size has been investigated. Temperature sensitivity or lower critical solution temperature (LCST) of the nanoparticles has been followed by Zeta Sizer as change in particle size. In order to determine the protein adsorption capacity of nanoparticles, adsorption experiments have been investigated as a function of temperature and PEG-EEM amount. The results showed that the adsorption capacity of...
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  • 甲基丙烯酸酯 蛋白质
  • adsorption 吸附
  • temperature 温度
  • comonomer 共聚用单体
  • particle 颗粒
  • protein 蛋白质
  • methacrylate 蛋白质
  • polymeric 聚合的
  • amount 总计
  • adsorbed 被吸附的
  • polymerization 聚合酌