Human zygote reconstruction by spindle, polar body or pronuclear transfer to treat repeated embryo fragmentation or embryo developmental arrest: The future is now
作者: Konstantinos A Economou
刊名: Journal of Gynecological Research and Obstetrics, 2018, Vol.4 (3), pp.049-051
来源数据库: Peertechz Publications Private Limited
DOI: 10.17352/jgro.000059
原始语种摘要: A common and very difficult issue to overcome as a clinical embryologist during an IVF cycle is the event of severe embryonic fragmentation or, more rarely, full developmental arrest. The current approach to bypass these phenomena is oocyte donation, but this raises several ethical concerns from the couple’s side, since the offspring will bear only 50% of the biological characteristics of the parents. Apart from spindle and polar body transfer, the emerging technique in order to overcome these obstacles is called Pronuclear Transfer (PNT). PNT is safest to perform with improved results than spindle or polar body transfer. In PNT, the two parental pronuclei are being transferred into a donor’s enucleated zygote and after a fusion process has been achieved, the newly constructed embryo may...
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  • embryo 
  • repeated 重复的
  • developmental 试验性的
  • zygote 合子
  • transfer 转换
  • polar 极线
  • spindle 纺锤体
  • offspring 后代
  • several 各自
  • fragmentation 破碎