Epidermal Growth Factor Receptor (EGFR) and Vascular Endothelial Growth Factor (VEGF) expression in Sinonasal Inverted Papillomas
作者: Mario Bilic Ena Klaric Lana Kovac-Bilic Selma Hodzic-RedzicSven Seiwerth
刊名: Archives of Otolaryngology and Rhinology, 2018, Vol.4 (4), pp.101-106
来源数据库: Peertechz Publications Private Limited
DOI: 10.17352/2455-1759.000086
关键词: PapillomaInvertedReceptorEpidermal Growth Factor Receptor (EGFR)Vascular Endothelial Growth Factor (VEGF)Head and neck neoplasms
原始语种摘要: The aim of this study was to evaluate the expression of Epidermal Growth Factor Receptor (EGFR) and Vascular Endothelial Growth Factor (VEGF) in patients with primary inverted papilloma (IP), recurrence of IP and carcinoma based on IP.The study was performed on an archived material of the 52 patients that were surgically treated because of the primary IP, recurrent IP and carcinoma that developed on the ground of IP on the Tertiary care University Center in the period of 18 years. The expression of the EGFR and VEGF were measured by an immunohistochemistry method using commercially available antibodies.There is a significant difference in expression of EGFR comparing primary IP to recurrence and squamous cell carcinoma (SCC) in the region of squamous and dysplastic epithelium, and also in...
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  • dysplastic 发育异常的
  • expression 表示
  • carcinoma 癌症
  • recurrence 循环
  • squamous 具鳞的
  • papilloma 乳头状瘤
  • Growth 生长
  • metaplastic 化生
  • primary 一次的
  • tumour 肿瘤