Pericyte plasticity – comparative investigation of the angiogenic and multilineage potential of pericytes from different human tissues
作者: M HerrmannJ J BaraC M SprecherU MenzelJ M JalowiecR OsingaA ScherberichM AliniS Verrier
作者单位: 1AO Research Institute Davos, Clavadelerstrasse 8, 7270 Davos Platz, Switzerland.sophie.verrier@aofoundation.org
刊名: Eur Cell Mater, 2016, Vol.31 , pp.236-249
来源数据库: European Cells and Materials (eCM)
DOI: 10.22203/eCM.v031a16
原始语种摘要: Pericyte recruitment is essential for the stability of newly formed vessels. It was also suggested that pericytes represent common ancestor cells giving rise to mesenchymal stem cells (MSCs) in the adult. Here, we systematically investigated pericytes and MSCs from different human tissues in terms of their angiogenic and multilineage differentiation potential in vitro in order to assess the suitability of the different cell types for the regeneration of vascularised tissues. Magnetic-activated cell sorting (MACS®) was used to enrich CD34-CD146+ pericytes from adipose tissue (AT) and bone marrow (BM). The multilineage potential of pericytes was assessed by testing their capability to differentiate towards osteogenic, adipogenic and chondrogenic lineage in vitro. Pericytes and endothelial...
全文获取路径: European Cells and Materials (eCM)  (合作)
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影响因子:4.558 (2012)

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关键词翻译
关键词翻译
  • potential 
  • osteogenic 成骨的
  • different 不相同的
  • comparative 比较的
  • angiogenic 血管由来的
  • mesenchymal 间叶细胞的
  • human 人的
  • adipogenic 生脂的
  • cells 麻风细胞
  • plasticity 可塑性