Woven bone overview: structural classification based on its integral role in developmental, repair and pathological bone formation throughout vertebrate groups
作者: F ShapiroJ Y Wu
作者单位: 1Stanford University School of Medicine, Department of Medicine/Endocrinology, Palo Alto, CA, USA.muskoka4@stanford.edu
刊名: Eur Cell Mater, 2019, Vol.38 , pp.137-167
来源数据库: European Cells and Materials (eCM)
DOI: 10.22203/eCM.v038a11
原始语种摘要: Cortical bone development is characterised by initial formation of woven bone followed by deposition of lamellar bone on the woven scaffold. This occurs in normal bone formation as an integral obligate self-assembly pattern throughout all vertebrate groups, with specific temporal and spatial features. It also occurs in repair bone, modified by the biophysical/mechanical environment, and in pathological bone, modified by the specific disorder and its severity. Two spatially distinct osteoblast cell populations synthesise woven and lamellar bone: mesenchymal osteoblasts surround themselves circumferentially with collagen in a random array to form woven bone; surface osteoblasts align themselves in a linear array on the woven bone surface (or adjacent lamellar bone) to synthesise...
全文获取路径: European Cells and Materials (eCM) 
影响因子:4.558 (2012)

  • woven 编织
  • formation 建造
  • lamellar 层纹状的
  • overview 概观
  • vertebrate 有脊椎的
  • structural 构造
  • pathological 病理学的
  • themselves 本身
  • surround 围绕
  • mechanical 机械的