Pyrocarbon versus cobalt-chromium in the context of spherical interposition implants: an in vitro study on cultured chondrocytes
作者: A HannounG OuenzerfiL BrizuelaS MebarekC BougaultM HasslerY BerthierA-M Trunfio-Sfarghiu
作者单位: 1INSA of Lyon, Bâtiment Sophie Germain 27bis, Avenue Jean Capelle, F69621, Villeurbanne,
刊名: Eur Cell Mater, 2019, Vol.37 , pp.1-15
来源数据库: European Cells and Materials (eCM)
DOI: 10.22203/eCM.v037a01
原始语种摘要: In the context of shoulder surgical replacement, a new generation of spherical interposition implants has been developed, with the implant being a mobile spacer rubbing against the glenoid cartilage and humeral bone cavity. The aim of the present study was to compare pyrocarbon (PyC) versus cobalt-chromium (CoCr) implants, regarding preservation and regeneration of the surrounding tissues. The effect of the biomaterials on chondrocytes was analysed in vitro. Murine primary chondrocytes were grown on discs made of PyC or CoCr using two culture media to mimic either cartilage-like or bone-like conditions (CLC or BLC). Chondrocytes did grow on PyC and CoCr without alteration in cell viability or manifestation of cytotoxicity. The tissue-like cell membranes grown under BLC were examined for...
全文获取路径: European Cells and Materials (eCM)  (合作)
影响因子:4.558 (2012)

  • spherical 球的
  • cobalt 
  • interposition 插补术
  • pyrocarbon 高温碳
  • grown 生长
  • modulus 系数
  • compare 比较
  • plastic 可塑性的
  • study 学习
  • mechanical 机械的