Design, characterisation and in vivo testing of a new, adjustable stiffness, external fixator for the rat femur
作者: V GlattC H EvansR Matthys
作者单位: 1Beth Israel Deaconess Medical Center, Center for Advanced Orthopaedic Studies, 330 Brookline Avenue, RN115, Boston, MA 02215, USA.vglatt@bidmc.harvard.edu
刊名: Eur Cell Mater, 2012, Vol.23 , pp.289-299
来源数据库: European Cells and Materials (eCM)
DOI: 10.22203/eCM.v023a22
原始语种摘要: Very little is known about the influence of the mechanical environment on the healing of large segmental defects. This partly reflects the lack of standardised, well characterised technologies to enable such studies. Here we report the design, construction and characterisation of a novel external fixator for use in conjunction with rat femoral defects. This device not only imposes a predetermined axial stiffness on the lesion, but also enables the stiffness to be changed during the healing process. The main frame of the fixator consists of polyethylethylketone with titanium alloy mounting pins. The stiffness of the fixator is determined by interchangeable connection elements of different thicknesses. Fixators were shown to stabilise 5 mm femoral defects in rats in vivo for at least 8...
全文获取路径: European Cells and Materials (eCM)  (合作)
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影响因子:4.558 (2012)

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关键词翻译
关键词翻译
  • fixator 介体
  • stiffness 刚性
  • femur 股骨
  • femoral 股的
  • external 外部的
  • healing 加硫
  • inserting 插入
  • segmental 部分的
  • predetermined 修]预定[置
  • altering 修改