Autologous bilayered self-assembled skin substitutes (SASSs) as permanent grafts: a case series of 14 severely burned patients indicating clinical effectiveness
作者: L GermainD LaroucheB NedelecI PerreaultL DuranceauP BortoluzziC Beaudoin CloutierH GenestL Caouette-LabergeA DumasA BussièreE BoghossianJ KanevskyY LeclercJ LeeM T NguyenV BernierB M KnoppersV J MoulinF A Auger
作者单位: 1CHU de Québec-Université Laval, LOEX, Aile-R, 1401 18ième Rue, Quebec, Quebec, G1J 1Z4,
刊名: Eur Cell Mater, 2018, Vol.36 , pp.128-141
来源数据库: European Cells and Materials (eCM)
DOI: 10.22203/eCM.v036a10
原始语种摘要: Split-thickness skin autografts (AGs) are the standard surgical treatment for severe burn injuries. However, the treatment of patients with substantial skin loss is limited by the availability of donor sites for skin harvesting. As an alternative to skin autografts, our research group developed autologous self-assembled skin substitutes (SASSs), allowing the replacement of both dermis and epidermis in a single surgical procedure. The aim of the study was to assess the clinical outcome of the SASSs as a permanent coverage for full-thickness burn wounds. Patients were recruited through the Health Canada’s Special Access Program. SASSs were grafted on debrided full-thickness wounds according to similar protocols used for AGs. The graft-take and the persistence of the SASS epithelium over...
全文获取路径: European Cells and Materials (eCM) 
影响因子:4.558 (2012)

  • thickness 厚度
  • permanent 永久的
  • standard 标准
  • according 按照
  • successful 成功的
  • total 总和
  • bilayered 双层的
  • years 年代
  • quality 品质
  • treatment 处理